| Pair Name | Isoquercitrin, TNF-related apoptosis inducing ligand | ||
| Phytochemical Name | Isoquercitrin (PubChem CID: 5280804 ) | ||
| Anticancer drug Name | TNF-related apoptosis inducing ligand (PubChem CID: / ) | ||
| Structure of Phytochemical |
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| Structure of Anticancer Drug |
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| Pair Name | Isoquercitrin, TNF-related apoptosis inducing ligand | |||
| Disease Info | [ICD-11: 2C77] | Cervical cancer | Investigative | |
| Biological Phenomena | Induction-->Apoptosis | |||
| Gene Regulation | Up-regulation | Expression | TNFRSF10A | hsa8797 |
| Up-regulation | Expression | TNFRSF10B | hsa8795 | |
| In Vitro Model | SiHa | Human papillomavirus-related cervical squamous cell carcinoma | Homo sapiens (Human) | CVCL_0032 |
| Result | We found that isoquercitrin enhances the mRNA expression of TRAIL-Rs, but the percentage of apoptosis was meager, possibly due to the influence of other anti-apoptotic proteins. | |||
| No. | Title | Href |
|---|---|---|
| 1 | Effects of A.marina-Derived Isoquercitrin on TNF-Related Apoptosis-Inducing Ligand Receptor (TRAIL-R) Expression and Apoptosis Induction in Cervical Cancer Cells. Appl Biochem Biotechnol. 2017 Jun;182(2):697-707. doi: 10.1007/s12010-016-2355-6. | Click |
